This work is licensed under a Creative Commons Attribution 4.0 International License.
Cyclo(Pro-Leu), S.sp. DKP-PL, Gancidin W
General Information
DCTPep ID DCTPep03961
Peptide Name Cyclo(Pro-Leu), S.sp. DKP-PL, Gancidin W
Sequence PL
Sequence Length 2
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
ACP Tumor active peptide
Activity Information
| Cell Line | Disease | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|
| PANC-1 | Pancreatic ductal adenocarcinoma | 14% Inhibition=20µM | MTT assay | Not available | 1 |
| HeLa S3 | Breast cancer | 41% Inhibition=20µM | MTT assay | Not available | 1 |
| Eca 109 | Esophageal squamous cell carcinoma; Squamous cell carcinoma of the esophagus | 55% Inhibition=20µM | MTT assay | Not available | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Amide bond: Pro1<--->Leu2
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula Not Applicable
Absent amino acids Not Applicable
Theoretical pI Not Applicable
Acidic residues Not Applicable
Basic residues Not Applicable
Polar residues Not Applicable
Molecular weight (Average) Not Applicable
Molecular weight (Monoisotopic) Not Applicable
Common amino acids Not Applicable
Net charge Not Applicable
Instability index (II) Not Applicable
Aliphatic index Not Applicable
Grand average of hydropathicity (GRAVY) Not Applicable
Half Life
Not Applicable
Extinction coefficients
Not Applicable
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30270742
Title Chemical constituents from the deep sea-derived Streptomyces xiamenensis MCCC 1A01570 and their effects on RXRα transcriptional regulation
Doi 10.1080/14786419.2018.1508148
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 15017
This work is licensed under a Creative Commons Attribution 4.0 International License.