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Z8
General Information
DCTPep ID DCTPep03980
Peptide Name Z8
Sequence KWAKKAAKWAKKAAKWAKKAA
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C114H185N33O22
Absent amino acids CDEFGHILMNPQRSTVY
Theoretical pI 10.90
Acidic residues 0
Basic residues 9
Polar residues 0
Molecular weight (Average) 2369.93
Molecular weight (Monoisotopic) 2368.44
Common amino acids AK
Net charge 9
Instability index (II) -11.95
Aliphatic index 42.86
Grand average of hydropathicity (GRAVY) -1.029
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 16500
Abs 0.1% (=1 g/l) 6.962
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22057278
Title Relative spatial positions of tryptophan and cationic residues in helical membrane-active peptides determine their cytotoxicity
Doi Not available
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 15140
This work is licensed under a Creative Commons Attribution 4.0 International License.