This work is licensed under a Creative Commons Attribution 4.0 International License.
GBV-A10 [P16L]
General Information
DCTPep ID DCTPep04003
Peptide Name GBV-A10 [P16L]
Sequence CWVRLGRYLLRRLKTLFT
Sequence Length 18
UniProt ID O41892
PubChem CID 71597843
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C107H176N32O22S1
Absent amino acids ADEHIMNPQS
Theoretical pI 11.56
Acidic residues 0
Basic residues 5
Polar residues 5
Molecular weight (Average) 2294.84
Molecular weight (Monoisotopic) 2293.34
Common amino acids L
Net charge 5
Instability index (II) 51.5
Aliphatic index 124.44
Grand average of hydropathicity (GRAVY) 0.144
Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 3.046, assuming all pairs of Cys residues form cystines
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 3.046, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23175359
Title Screening and Rational Design of Hepatitis C Virus Entry Inhibitory Peptides Derived From GB Virus A NS5A
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 15442
This work is licensed under a Creative Commons Attribution 4.0 International License.