Ocellatin-3N

General Information


DCTPep ID  DCTPep04031

Peptide Name   Ocellatin-3N

Sequence  GIFDVLKNLAKGVITSLAS

Sequence Length  19

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C89H152N22O26

Absent amino acids  CEHMPQRWY

Theoretical pI  8.59

Acidic residues  1

Basic residues  2

Polar residues  6

Molecular weight (Average)  1946.32

Molecular weight (Monoisotopic)  1945.12

Common amino acids  L

Net charge  1

Instability index (II)  2.56

Aliphatic index  143.68

Grand average of hydropathicity (GRAVY)  0.911

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 36426386

Title  Antimicrobial, cytotoxic, and insulin-releasing activities of the amphibian host-defense peptide ocellatin-3N and its L-lysine-substituted analogs

Doi Not available

Year  2022

Literature 2

Pubmed ID 33092132

Title  Peptidomic Analysis of Skin Secretions of the Caribbean Frogs Leptodactylus insularum and Leptodactylus nesiotus (Leptodactylidae) Identifies an Ocellatin with Broad

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  16392

DCTPep is developed by Dr.Zheng's team.