This work is licensed under a Creative Commons Attribution 4.0 International License.
Citropin 1.1 [G15P]-G, Citropin A
General Information
DCTPep ID DCTPep04049
Peptide Name Citropin 1.1 [G15P]-G, Citropin A
Sequence GLFDVIKKVASVIGPLG
Sequence Length 17
UniProt ID P81835
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C81H137N19O21
Absent amino acids CEHMNQRTWY
Theoretical pI 8.59
Acidic residues 1
Basic residues 2
Polar residues 4
Molecular weight (Average) 1713.09
Molecular weight (Monoisotopic) 1712.02
Common amino acids GV
Net charge 1
Instability index (II) 6.68
Aliphatic index 148.82
Grand average of hydropathicity (GRAVY) 1.112
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title The design and anticancer activity of a citropin1.1 hybrid peptide with selective activity against highly invasive metastatic cell lines
Year 2019
Literature 2
Pubmed ID 15203252
Title Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance
Doi Not available
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16496
This work is licensed under a Creative Commons Attribution 4.0 International License.