This work is licensed under a Creative Commons Attribution 4.0 International License.
R-DIM-P-LF11
General Information
DCTPep ID DCTPep04052
Peptide Name R-DIM-P-LF11
Sequence FQWQRNIRKVRPRVKRINRQWQF
Sequence Length 23
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C143H227N51O30
Absent amino acids ACDEGHLMSTY
Theoretical pI 12.70
Acidic residues 0
Basic residues 8
Polar residues 2
Molecular weight (Average) 3140.7
Molecular weight (Monoisotopic) 3138.78
Common amino acids R
Net charge 8
Instability index (II) 53.46
Aliphatic index 59.13
Grand average of hydropathicity (GRAVY) -1.574
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 3.502
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Two Novel Anticancer Peptides from Aurein 1.2
Year 2011
Literature 2
Pubmed ID 15203252
Title Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance
Doi Not available
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16501
This work is licensed under a Creative Commons Attribution 4.0 International License.