This work is licensed under a Creative Commons Attribution 4.0 International License.
R-DIM-P-LF11-215
General Information
DCTPep ID DCTPep04053
Peptide Name R-DIM-P-LF11-215
Sequence FWRIRIRRPRRIRIRWF
Sequence Length 17
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C117H187N43O18
Absent amino acids ACDEGHKLMNQSTVY
Theoretical pI 12.85
Acidic residues 0
Basic residues 8
Polar residues 0
Molecular weight (Average) 2484.05
Molecular weight (Monoisotopic) 2482.5
Common amino acids R
Net charge 8
Instability index (II) 117.39
Aliphatic index 91.76
Grand average of hydropathicity (GRAVY) -0.929
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 4.428
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32151609
Title Design of human lactoferricin derived antitumor peptides-activity and specificity against malignant melanoma in 2D and 3D model studies
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16502
This work is licensed under a Creative Commons Attribution 4.0 International License.