This work is licensed under a Creative Commons Attribution 4.0 International License.
R-DIM-LF11-334-LF11-334
General Information
DCTPep ID DCTPep04056
Peptide Name R-DIM-LF11-334-LF11-334
Sequence PWRIRIRRRRIRIRWPPWRIRIRR
Sequence Length 24
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C156H263N63O25
Absent amino acids ACDEFGHKLMNQSTVY
Theoretical pI 13.04
Acidic residues 0
Basic residues 12
Polar residues 0
Molecular weight (Average) 3421.21
Molecular weight (Monoisotopic) 3419.12
Common amino acids R
Net charge 12
Instability index (II) 134.54
Aliphatic index 97.50
Grand average of hydropathicity (GRAVY) -1.438
Half Life
>20 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
? (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 16500
Abs 0.1% (=1 g/l) 4.823
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32151609
Title Design of human lactoferricin derived antitumor peptides-activity and specificity against malignant melanoma in 2D and 3D model studies
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16505
This work is licensed under a Creative Commons Attribution 4.0 International License.