R-DIM-LF11-334-LF11-334

General Information


DCTPep ID  DCTPep04056

Peptide Name   R-DIM-LF11-334-LF11-334

Sequence  PWRIRIRRRRIRIRWPPWRIRIRR

Sequence Length  24

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C156H263N63O25

Absent amino acids  ACDEFGHKLMNQSTVY

Theoretical pI  13.04

Acidic residues  0

Basic residues  12

Polar residues  0

Molecular weight (Average)  3421.21

Molecular weight (Monoisotopic)  3419.12

Common amino acids  R

Net charge  12

Instability index (II)  134.54

Aliphatic index  97.50

Grand average of hydropathicity (GRAVY)  -1.438

Half Life 
  >20 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  ? (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 16500
  Abs 0.1% (=1 g/l) 4.823

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32151609

Title  Design of human lactoferricin derived antitumor peptides-activity and specificity against malignant melanoma in 2D and 3D model studies

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  16505

DCTPep is developed by Dr.Zheng's team.