AcrAP1 [S4,11,15K;P7K], AP1-Z5b

General Information


DCTPep ID  DCTPep04058

Peptide Name   AcrAP1 [S4,11,15K;P7K], AP1-Z5b

Sequence  FLFKLIKHAIKGLIKAFK

Sequence Length  18

UniProt ID  A0A0A1I6E7 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C107H175N25O19

Absent amino acids  CDEMNPQRSTVWY

Theoretical pI  10.60

Acidic residues  0

Basic residues  6

Polar residues  1

Molecular weight (Average)  2115.72

Molecular weight (Monoisotopic)  2114.35

Common amino acids  K

Net charge  6

Instability index (II)  -30.84

Aliphatic index  141.11

Grand average of hydropathicity (GRAVY)  0.767

Half Life 
  1.1 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31909181

Title  In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  16518

DCTPep is developed by Dr.Zheng's team.