Lactotransferrin (590-619), Lactofungin

General Information


DCTPep ID  DCTPep04065

Peptide Name   Lactotransferrin (590-619), Lactofungin

Sequence  LLCLDGTRKPVTEAQSCHLAVAPNHAVVSR

Sequence Length  30

UniProt ID  P24627 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C136H229N43O41S2

Absent amino acids  FIMWY

Theoretical pI  8.08

Acidic residues  2

Basic residues  5

Polar residues  8

Molecular weight (Average)  3186.7

Molecular weight (Monoisotopic)  3184.66

Common amino acids  ALV

Net charge  3

Instability index (II)  69.97

Aliphatic index  104.00

Grand average of hydropathicity (GRAVY)  0.143

Half Life 
  5.5 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 125
  Abs 0.1% (=1 g/l) 0.039, assuming all pairs of Cys residues form cystines
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32690642

Title  Lactoferrin-Derived Peptide Lactofungin Is Potently Synergistic with Amphotericin B

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  16556

DCTPep is developed by Dr.Zheng's team.