This work is licensed under a Creative Commons Attribution 4.0 International License.
Lactotransferrin (590-619), Lactofungin
General Information
DCTPep ID DCTPep04065
Peptide Name Lactotransferrin (590-619), Lactofungin
Sequence LLCLDGTRKPVTEAQSCHLAVAPNHAVVSR
Sequence Length 30
UniProt ID P24627
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C136H229N43O41S2
Absent amino acids FIMWY
Theoretical pI 8.08
Acidic residues 2
Basic residues 5
Polar residues 8
Molecular weight (Average) 3186.7
Molecular weight (Monoisotopic) 3184.66
Common amino acids ALV
Net charge 3
Instability index (II) 69.97
Aliphatic index 104.00
Grand average of hydropathicity (GRAVY) 0.143
Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.039, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32690642
Title Lactoferrin-Derived Peptide Lactofungin Is Potently Synergistic with Amphotericin B
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16556
This work is licensed under a Creative Commons Attribution 4.0 International License.