General Information


DCTPep ID  DCTPep04072

Peptide Name  

Sequence  DGRCLLIIKLAKLAKKLAKLAK

Sequence Length  22

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C111H207N31O25S1

Absent amino acids  EFHMNPQSTVWY

Theoretical pI  10.31

Acidic residues  1

Basic residues  7

Polar residues  2

Molecular weight (Average)  2408.12

Molecular weight (Monoisotopic)  2406.56

Common amino acids  KL

Net charge  6

Instability index (II)  -1

Aliphatic index  160.00

Grand average of hydropathicity (GRAVY)  0.441

Half Life 
  1.1 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all pairs of Cys residues form cystines
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 23326440

Title  Antitumor activity of antimicrobial peptides containing CisoDGRC in CD13 negative breast cancer cells

Doi Not available

Year  2013

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  16628

DCTPep is developed by Dr.Zheng's team.