This work is licensed under a Creative Commons Attribution 4.0 International License.
General Information
DCTPep ID DCTPep04072
Peptide Name
Sequence DGRCLLIIKLAKLAKKLAKLAK
Sequence Length 22
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C111H207N31O25S1
Absent amino acids EFHMNPQSTVWY
Theoretical pI 10.31
Acidic residues 1
Basic residues 7
Polar residues 2
Molecular weight (Average) 2408.12
Molecular weight (Monoisotopic) 2406.56
Common amino acids KL
Net charge 6
Instability index (II) -1
Aliphatic index 160.00
Grand average of hydropathicity (GRAVY) 0.441
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23326440
Title Antitumor activity of antimicrobial peptides containing CisoDGRC in CD13 negative breast cancer cells
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16628
This work is licensed under a Creative Commons Attribution 4.0 International License.