This work is licensed under a Creative Commons Attribution 4.0 International License.
Myotoxin II (105-117)[Y3,6W][Y5K,P9W,C11A], PEM-2 [W5K,A9W]
General Information
DCTPep ID DCTPep04073
Peptide Name Myotoxin II (105-117)[Y3,6W][Y5K,P9W,C11A], PEM-2 [W5K,A9W]
Sequence KKWRKWLKWLAKK
Sequence Length 13
UniProt ID P24605
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C90H143N25O14
Absent amino acids CDEFGHIMNPQSTVY
Theoretical pI 11.43
Acidic residues 0
Basic residues 7
Polar residues 0
Molecular weight (Average) 1799.28
Molecular weight (Monoisotopic) 1798.12
Common amino acids K
Net charge 7
Instability index (II) 21.68
Aliphatic index 67.69
Grand average of hydropathicity (GRAVY) -1.631
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 16500
Abs 0.1% (=1 g/l) 9.170
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30447380
Title Repurposing azithromycin and rifampicin against Gram-negative pathogens by combination with peptide potentiators
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16784
This work is licensed under a Creative Commons Attribution 4.0 International License.