This work is licensed under a Creative Commons Attribution 4.0 International License.
Phylloseptin-PV1, PPV1
General Information
DCTPep ID DCTPep04090
Peptide Name Phylloseptin-PV1, PPV1
Sequence FLSLIPKIAGGIAALVKNL
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C93H160N22O22
Absent amino acids CDEHMQRTWY
Theoretical pI 10.00
Acidic residues 0
Basic residues 2
Polar residues 4
Molecular weight (Average) 1938.43
Molecular weight (Monoisotopic) 1937.21
Common amino acids L
Net charge 2
Instability index (II) 4
Aliphatic index 174.74
Grand average of hydropathicity (GRAVY) 1.400
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33193152
Title A Novel Amphibian Antimicrobial Peptide, Phylloseptin-PV1, Exhibits Effective Anti- staphylococcal Activity Without Inducing Either Hepatic or Renal Toxicity in Mice
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 16974
This work is licensed under a Creative Commons Attribution 4.0 International License.