PN-CATH2
General Information
DCTPep ID DCTPep04093
Peptide Name PN-CATH2
Sequence EGCNILCLLKRKVKAVKNVVKNVVKSVVG
Sequence Length 29
UniProt ID Not available
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C139H253N41O36S2
Absent amino acids DFHMPQTWY
Theoretical pI 10.05
Acidic residues 1
Basic residues 7
Polar residues 8
Molecular weight (Average) 3138.91
Molecular weight (Monoisotopic) 3136.87
Common amino acids V
Net charge 6
Instability index (II) 36.58
Aliphatic index 137.24
Grand average of hydropathicity (GRAVY) 0.441
Half Life
1 hours (mammalian reticulocytes, in vitro).
30 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.040, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33242568
Title Identification and characterization of novel bi-functional cathelicidins from the black-spotted frog (Pelophylax nigromaculata) with both anti-infective and antioxidant activities
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 17031