PN-CATH2

General Information


DCTPep ID  DCTPep04093

Peptide Name   PN-CATH2

Sequence  EGCNILCLLKRKVKAVKNVVKNVVKSVVG

Sequence Length  29

UniProt ID  Not available

PubChem CID  Not available

Origin  Animalia

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C139H253N41O36S2

Absent amino acids  DFHMPQTWY

Theoretical pI  10.05

Acidic residues  1

Basic residues  7

Polar residues  8

Molecular weight (Average)  3138.91

Molecular weight (Monoisotopic)  3136.87

Common amino acids  V

Net charge  6

Instability index (II)  36.58

Aliphatic index  137.24

Grand average of hydropathicity (GRAVY)  0.441

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  30 min (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 125
  Abs 0.1% (=1 g/l) 0.040, assuming all pairs of Cys residues form cystines
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 33242568

Title  Identification and characterization of novel bi-functional cathelicidins from the black-spotted frog (Pelophylax nigromaculata) with both anti-infective and antioxidant activities

Doi Not available

Year  2021

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  17031

DCTPep is developed by Dr.Zheng's team.