Peptide Libraray

C-Tritrpticin-C

General Information

DCTPep ID DCTPep04116

Peptide Name C-Tritrpticin-C

Sequence CVRRFPWWWPFLRRC

Sequence Length 15

UniProt ID P51524

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

Cancer therapy related peptides

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Cyclic

Disulfide/Other Bond Cys1<--->Cys15

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C102H142N30O16S2

Absent amino acids ADEGHIKMNQSTY

Theoretical pI 11.53

Acidic residues 0

Basic residues 4

Polar residues 2

Molecular weight (Average) 2108.56

Molecular weight (Monoisotopic) 2107.07

Common amino acids R

Net charge 4

Instability index (II) 117.28

Aliphatic index 45.33

Grand average of hydropathicity (GRAVY) -0.353

Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 16625
Abs 0.1% (=1 g/l) 7.885, assuming all pairs of Cys residues form cystines
Ext. coefficient 16500
Abs 0.1% (=1 g/l) 7.825, assuming all Cys residues are reduced

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 32126228

Title Selective anticancer activity of Synthetic peptide peptides derived from the host defence peptide tritrpticin

Doi Not available

Year 2020

Literature 2

Pubmed ID 26781579

Title Cyclic Tritrpticin Analogs with Distinct Biological Activities

Doi Not available

Year 2011

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available

External Code

DBAASP ID 17182