Cecropin A-like 4 (3-18)[K2W;G5,12W;E9W;Q13K;H14N;T15W]

General Information


DCTPep ID  DCTPep04131

Peptide Name   Cecropin A-like 4 (3-18)[K2W;G5,12W;E9W;Q13K;H14N;T15W]

Sequence  LWKIWKKIWRVWKNWR

Sequence Length  16

UniProt ID  A0A1I8M6I1 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C118H172N32O18

Absent amino acids  ACDEFGHMPQSTY

Theoretical pI  12.03

Acidic residues  0

Basic residues  6

Polar residues  1

Molecular weight (Average)  2326.87

Molecular weight (Monoisotopic)  2325.35

Common amino acids  W

Net charge  6

Instability index (II)  7.08

Aliphatic index  91.25

Grand average of hydropathicity (GRAVY)  -0.975

Half Life 
  5.5 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 27500
  Abs 0.1% (=1 g/l) 11.818

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 33401476

Title  Novel Cecropin-4 Derived Peptides against Methicillin-Resistant Staphylococcus aureus

Doi Not available

Year  2021

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  17516

DCTPep is developed by Dr.Zheng's team.