This work is licensed under a Creative Commons Attribution 4.0 International License.
Cecropin A-like 4 (3-18)[K2W;G5,12W;E9W;Q13K;H14N;T15W]
General Information
DCTPep ID DCTPep04131
Peptide Name Cecropin A-like 4 (3-18)[K2W;G5,12W;E9W;Q13K;H14N;T15W]
Sequence LWKIWKKIWRVWKNWR
Sequence Length 16
UniProt ID A0A1I8M6I1
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C118H172N32O18
Absent amino acids ACDEFGHMPQSTY
Theoretical pI 12.03
Acidic residues 0
Basic residues 6
Polar residues 1
Molecular weight (Average) 2326.87
Molecular weight (Monoisotopic) 2325.35
Common amino acids W
Net charge 6
Instability index (II) 7.08
Aliphatic index 91.25
Grand average of hydropathicity (GRAVY) -0.975
Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 27500
Abs 0.1% (=1 g/l) 11.818
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33401476
Title Novel Cecropin-4 Derived Peptides against Methicillin-Resistant Staphylococcus aureus
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 17516
This work is licensed under a Creative Commons Attribution 4.0 International License.