This work is licensed under a Creative Commons Attribution 4.0 International License.
General Information
DCTPep ID DCTPep04164
Peptide Name
Sequence GKLRLIKKLWVKKWKKKGWKA
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C129H216N36O22
Absent amino acids CDEFHMNPQSTY
Theoretical pI 11.53
Acidic residues 0
Basic residues 10
Polar residues 2
Molecular weight (Average) 2623.36
Molecular weight (Monoisotopic) 2621.69
Common amino acids K
Net charge 10
Instability index (II) 10.22
Aliphatic index 92.86
Grand average of hydropathicity (GRAVY) -1.010
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 16500
Abs 0.1% (=1 g/l) 6.290
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33677023
Title Dual antimicrobial and anticancer activity of a novel synthetic α-helical antimicrobial peptide
Doi 10.1016/j.ejps.2021.105784
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 17934
This work is licensed under a Creative Commons Attribution 4.0 International License.