General Information


DCTPep ID  DCTPep04168

Peptide Name  

Sequence  VKAWAKVLKGFGKLLKGFGKL

Sequence Length  21

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C113H186N28O22

Absent amino acids  CDEHIMNPQRSTY

Theoretical pI  10.70

Acidic residues  0

Basic residues  6

Polar residues  4

Molecular weight (Average)  2288.89

Molecular weight (Monoisotopic)  2287.43

Common amino acids  K

Net charge  6

Instability index (II)  -35.39

Aliphatic index  111.43

Grand average of hydropathicity (GRAVY)  0.329

Half Life 
  100 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 5500
  Abs 0.1% (=1 g/l) 2.403

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30506920

Title  Simulated Molecular Evolution for Anticancer Peptide Design

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  17986

DCTPep is developed by Dr.Zheng's team.