General Information
DCTPep ID DCTPep04170
Peptide Name
Sequence IRAWAKVLKGVGKILKGVGRW
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C111H187N33O22
Absent amino acids CDEFHMNPQSTY
Theoretical pI 12.03
Acidic residues 0
Basic residues 6
Polar residues 4
Molecular weight (Average) 2335.91
Molecular weight (Monoisotopic) 2334.45
Common amino acids GK
Net charge 6
Instability index (II) 2.43
Aliphatic index 125.24
Grand average of hydropathicity (GRAVY) 0.229
Half Life
20 hours (mammalian reticulocytes, in vitro).
30 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 4.709
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30506920
Title Simulated Molecular Evolution for Anticancer Peptide Design
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 17988