This work is licensed under a Creative Commons Attribution 4.0 International License.
Jelleine-1 [K3R;I4,6L;S5R;H7R]
General Information
DCTPep ID DCTPep04181
Peptide Name Jelleine-1 [K3R;I4,6L;S5R;H7R]
Sequence PFRLRLRL
Sequence Length 8
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C50H87N17O9
Absent amino acids ACDEGHIKMNQSTVWY
Theoretical pI 12.30
Acidic residues 0
Basic residues 3
Polar residues 0
Molecular weight (Average) 1070.35
Molecular weight (Monoisotopic) 1069.69
Common amino acids LR
Net charge 3
Instability index (II) 80.97
Aliphatic index 146.25
Grand average of hydropathicity (GRAVY) -0.113
Half Life
>20 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
? (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33878564
Title An optimized analog of antimicrobial peptide Jelleine-1 shows enhanced antimicrobial activity against multidrug resistant P aeruginosa and negligible toxicity in vitro and in vivo
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18223
This work is licensed under a Creative Commons Attribution 4.0 International License.