This work is licensed under a Creative Commons Attribution 4.0 International License.
Dermaseptin-TO, Dermaseptin-1
General Information
DCTPep ID DCTPep04188
Peptide Name Dermaseptin-TO, Dermaseptin-1
Sequence ALWKDLLKNVGIAAGKAALNKVTDMVNQ
Sequence Length 28
UniProt ID P85523
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C133H225N37O38S1
Absent amino acids CEFHPRSY
Theoretical pI 9.53
Acidic residues 2
Basic residues 4
Polar residues 6
Molecular weight (Average) 2982.53
Molecular weight (Monoisotopic) 2980.65
Common amino acids A
Net charge 2
Instability index (II) 5.67
Aliphatic index 118.57
Grand average of hydropathicity (GRAVY) 0.150
Half Life
4.4 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 1.844
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33582221
Title In vitro activities of a novel antimicrobial peptide isolated from phyllomedusa tomopterna
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18370
This work is licensed under a Creative Commons Attribution 4.0 International License.