Euryjanicin A

General Information


DCTPep ID  DCTPep04219

Peptide Name   Euryjanicin A

Sequence  WPISFVP

Sequence Length  7

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  NCB: Trp1<--->Pro7

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C44H60N8O9

Absent amino acids  ACDEGHKLMNQRTY

Theoretical pI  5.52

Acidic residues  0

Basic residues  0

Polar residues  1

Molecular weight (Average)  845.01

Molecular weight (Monoisotopic)  844.45

Common amino acids  P

Net charge  0

Instability index (II)  36.09

Aliphatic index  97.14

Grand average of hydropathicity (GRAVY)  0.943

Half Life 
  2.8 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 5500
  Abs 0.1% (=1 g/l) 6.509

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 19743810

Title  Isolation and structural elucidation of euryjanicins B-D, proline-containing cycloheptapeptides from the Caribbean marine sponge Prosuberites laughlini

Doi Not available

Year  2009

Literature 2

Pubmed ID 20161148

Title  Euryjanicin A: a new cycloheptapeptide from the Caribbean marine sponge Prosuberites laughlini

Doi Not available

Year  2009

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18505

DCTPep is developed by Dr.Zheng's team.