This work is licensed under a Creative Commons Attribution 4.0 International License.
Dermaseptin-AC
General Information
DCTPep ID DCTPep04243
Peptide Name Dermaseptin-AC
Sequence GMFTNMLKGIGKLAGKAALGAVKTLA
Sequence Length 26
UniProt ID Not available
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C115H201N31O30S2
Absent amino acids CDEHPQRSWY
Theoretical pI 10.48
Acidic residues 0
Basic residues 4
Polar residues 8
Molecular weight (Average) 2562.17
Molecular weight (Monoisotopic) 2560.46
Common amino acids AG
Net charge 4
Instability index (II) -20.13
Aliphatic index 105.38
Grand average of hydropathicity (GRAVY) 0.654
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34908502
Title In Vitro and In Vivo Studies on the Antibacterial Activity and Safety of a New Antimicrobial Peptide Dermaseptin-AC
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18625
This work is licensed under a Creative Commons Attribution 4.0 International License.