This work is licensed under a Creative Commons Attribution 4.0 International License.
Basic phospholipase A2 Ceg-N6 (99-110), pCergo
General Information
DCTPep ID DCTPep04259
Peptide Name Basic phospholipase A2 Ceg-N6 (99-110), pCergo
Sequence NLRTYKKRYMFY
Sequence Length 12
UniProt ID Q6EER5
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C79H119N21O18S1
Absent amino acids ACDEGHIPQSVW
Theoretical pI 10.17
Acidic residues 0
Basic residues 4
Polar residues 5
Molecular weight (Average) 1683
Molecular weight (Monoisotopic) 1681.88
Common amino acids Y
Net charge 4
Instability index (II) 109.88
Aliphatic index 32.50
Grand average of hydropathicity (GRAVY) -1.367
Half Life
1.4 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 4470
Abs 0.1% (=1 g/l) 2.656
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34130109
Title Dissection of phospholipases A 2 reveals multifaceted peptides targeting cancer cells, Leishmania and bacteria
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18751
This work is licensed under a Creative Commons Attribution 4.0 International License.