Basic phospholipase A2 BmjeTX-I (103-119), pBmje
General Information
DCTPep ID DCTPep04261
Peptide Name Basic phospholipase A2 BmjeTX-I (103-119), pBmje
Sequence YNKKYRYHLKSCKKADK
Sequence Length 17
UniProt ID P86803
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C98H157N29O25S1
Absent amino acids EFGIMPQTVW
Theoretical pI 9.92
Acidic residues 1
Basic residues 8
Polar residues 6
Molecular weight (Average) 2173.56
Molecular weight (Monoisotopic) 2172.16
Common amino acids K
Net charge 7
Instability index (II) 20.41
Aliphatic index 28.82
Grand average of hydropathicity (GRAVY) -2.041
Half Life
2.8 hours (mammalian reticulocytes, in vitro).
10 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 4470
Abs 0.1% (=1 g/l) 2.057, assuming all pairs of Cys residues form cystines
Ext. coefficient 4470
Abs 0.1% (=1 g/l) 2.057, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34130109
Title Dissection of phospholipases A 2 reveals multifaceted peptides targeting cancer cells, Leishmania and bacteria
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 18753