Basic phospholipase A2 BmjeTX-I (103-119), pBmje

General Information


DCTPep ID  DCTPep04261

Peptide Name   Basic phospholipase A2 BmjeTX-I (103-119), pBmje

Sequence  YNKKYRYHLKSCKKADK

Sequence Length  17

UniProt ID  P86803 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C98H157N29O25S1

Absent amino acids  EFGIMPQTVW

Theoretical pI  9.92

Acidic residues  1

Basic residues  8

Polar residues  6

Molecular weight (Average)  2173.56

Molecular weight (Monoisotopic)  2172.16

Common amino acids  K

Net charge  7

Instability index (II)  20.41

Aliphatic index  28.82

Grand average of hydropathicity (GRAVY)  -2.041

Half Life 
  2.8 hours (mammalian reticulocytes, in vitro).
  10 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 4470
  Abs 0.1% (=1 g/l) 2.057, assuming all pairs of Cys residues form cystines
  Ext. coefficient 4470
  Abs 0.1% (=1 g/l) 2.057, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 34130109

Title  Dissection of phospholipases A 2 reveals multifaceted peptides targeting cancer cells, Leishmania and bacteria

Doi Not available

Year  2021

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  18753

DCTPep is developed by Dr.Zheng's team.