This work is licensed under a Creative Commons Attribution 4.0 International License.
Brevinin-2MP
General Information
DCTPep ID DCTPep04355
Peptide Name Brevinin-2MP
Sequence GVITDTLKGVAKTVAAELLRKAHCKLTNSC
Sequence Length 30
UniProt ID Not available
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys24<--->Cys30
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C135H238N40O41S2
Absent amino acids FMPQWY
Theoretical pI 9.31
Acidic residues 2
Basic residues 6
Polar residues 10
Molecular weight (Average) 3141.74
Molecular weight (Monoisotopic) 3139.72
Common amino acids AKLT
Net charge 4
Instability index (II) 5.61
Aliphatic index 107.33
Grand average of hydropathicity (GRAVY) 0.210
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.040, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34975482
Title Antimicrobial and Anti-inflammatory Effects of a Novel Peptide From the Skin of Frog Microhyla pulchra
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19003
This work is licensed under a Creative Commons Attribution 4.0 International License.