Grasscarp interferon (137-156), GcIFN-20
General Information
DCTPep ID DCTPep04368
Peptide Name Grasscarp interferon (137-156), GcIFN-20
Sequence SYEKKINRHFKILKKNLKKK
Sequence Length 20
UniProt ID Q5KR62
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C118H203N35O27
Absent amino acids ACDGMPQTVW
Theoretical pI 10.53
Acidic residues 1
Basic residues 10
Polar residues 4
Molecular weight (Average) 2544.13
Molecular weight (Monoisotopic) 2542.56
Common amino acids K
Net charge 9
Instability index (II) -4.69
Aliphatic index 78.00
Grand average of hydropathicity (GRAVY) -1.605
Half Life
1.9 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.586
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 35289673
Title A Novel Antimicrobial Peptide Derived from Bony Fish IFN1 Exerts Potent Antimicrobial and Anti-Inflammatory Activity in Mammals
Doi Not available
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19122