Bacteriocin BaCf3
General Information
DCTPep ID DCTPep04376
Peptide Name Bacteriocin BaCf3
Sequence GNHDCCMGQLPKCMLGPGQGAATCQGK
Sequence Length 27
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys5<--->Cys13
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C107H177N35O35S6
Absent amino acids EFIRSVWY
Theoretical pI 7.89
Acidic residues 1
Basic residues 3
Polar residues 12
Molecular weight (Average) 2706.16
Molecular weight (Monoisotopic) 2704.15
Common amino acids G
Net charge 2
Instability index (II) 28.69
Aliphatic index 36.30
Grand average of hydropathicity (GRAVY) -0.363
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 250
Abs 0.1% (=1 g/l) 0.092, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title 3D Structure Elucidation and Appraisal of Mode of Action of a Bacteriocin BaCf3 with Anticancer Potential Produced by Marine Bacillus amyloliquefaciens BTSS3
Doi Not available
Year 2022
Literature 2
Pubmed ID 30863715
Title BaCf3: highly thermostable bacteriocin from Bacillus amyloliquefaciens BTSS3 antagonistic on food-borne pathogens
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19213