This work is licensed under a Creative Commons Attribution 4.0 International License.
Nigrocin-PN
General Information
DCTPep ID DCTPep04392
Peptide Name Nigrocin-PN
Sequence GLLGKILGAGKKVLCGVSGLC
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys15<--->Cys21
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C88H160N24O23S2
Absent amino acids DEFHMNPQRTWY
Theoretical pI 9.39
Acidic residues 0
Basic residues 3
Polar residues 9
Molecular weight (Average) 1986.51
Molecular weight (Monoisotopic) 1985.15
Common amino acids G
Net charge 3
Instability index (II) -1.52
Aliphatic index 143.81
Grand average of hydropathicity (GRAVY) 1.133
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.063, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 35606468
Title A novel antimicrobial peptide found in Pelophylax nigromaculatus
Doi 10.1186/s43141-022-00366-9
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19284
This work is licensed under a Creative Commons Attribution 4.0 International License.