Nigrocin-PN [C15,21L]
General Information
DCTPep ID DCTPep04393
Peptide Name Nigrocin-PN [C15,21L]
Sequence GLLGKILGAGKKVLLGVSGLL
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C94H172N24O23
Absent amino acids CDEFHMNPQRTWY
Theoretical pI 10.30
Acidic residues 0
Basic residues 3
Polar residues 7
Molecular weight (Average) 2006.55
Molecular weight (Monoisotopic) 2005.3
Common amino acids L
Net charge 3
Instability index (II) -1.52
Aliphatic index 180.95
Grand average of hydropathicity (GRAVY) 1.257
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 35606468
Title A novel antimicrobial peptide found in Pelophylax nigromaculatus
Doi 10.1186/s43141-022-00366-9
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19285