This work is licensed under a Creative Commons Attribution 4.0 International License.
Bactenecin-7 (1-23)[P5I,L18Y,P19F,F20M], Bac7PS
General Information
DCTPep ID DCTPep04397
Peptide Name Bactenecin-7 (1-23)[P5I,L18Y,P19F,F20M], Bac7PS
Sequence RRIRIRPPRLPRPRPRPYFMPRP
Sequence Length 23
UniProt ID P19661
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C135H226N50O25S1
Absent amino acids ACDEGHKNQSTVW
Theoretical pI 12.54
Acidic residues 0
Basic residues 9
Polar residues 1
Molecular weight (Average) 2981.66
Molecular weight (Monoisotopic) 2979.77
Common amino acids R
Net charge 9
Instability index (II) 95.8
Aliphatic index 50.87
Grand average of hydropathicity (GRAVY) -1.613
Half Life
1 hours (mammalian reticulocytes, in vitro).
2 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.500
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 35578204
Title Optimization of the antimicrobial peptide Bac7 by deep mutational scanning
Doi Not available
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19372
This work is licensed under a Creative Commons Attribution 4.0 International License.