This work is licensed under a Creative Commons Attribution 4.0 International License.
CrotAMP14
General Information
DCTPep ID DCTPep04401
Peptide Name CrotAMP14
Sequence KRLKKIFKKMIKIF
Sequence Length 14
UniProt ID U5KJM4
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C89H157N23O15S1
Absent amino acids ACDEGHNPQSTVWY
Theoretical pI 11.43
Acidic residues 0
Basic residues 7
Polar residues 0
Molecular weight (Average) 1821.43
Molecular weight (Monoisotopic) 1820.19
Common amino acids K
Net charge 7
Instability index (II) 20.86
Aliphatic index 111.43
Grand average of hydropathicity (GRAVY) -0.221
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32499582
Title Physicochemical-guided design of cathelicidin-derived peptides generates membrane active variants with therapeutic potential
Doi Not available
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19514
This work is licensed under a Creative Commons Attribution 4.0 International License.