This work is licensed under a Creative Commons Attribution 4.0 International License.
Microcionamide A
General Information
DCTPep ID DCTPep04428
Peptide Name Microcionamide A
Sequence VCIIIIC
Sequence Length 7
UniProt ID Not available
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys2<--->Cys7
N-terminal Modification Free
C-terminal Modification PEA
Other Modification None
Chiral L
Physicochemical Information
Formula C35H65N7O8S2
Absent amino acids ADEFGHKLMNPQRSTWY
Theoretical pI 5.48
Acidic residues 0
Basic residues 0
Polar residues 2
Molecular weight (Average) 776.06
Molecular weight (Monoisotopic) 775.43
Common amino acids I
Net charge 0
Instability index (II) 8.57
Aliphatic index 264.29
Grand average of hydropathicity (GRAVY) 3.886
Half Life
100 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.161, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 15176844
Title Microcionamides A and B, bioactive peptides from the philippine sponge Clathria (Thalysias) abietina
Doi Not available
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19755
This work is licensed under a Creative Commons Attribution 4.0 International License.