Peptide Libraray

Cecropin A (1-7)+Melittin (2-9)-C, CAMA

General Information

DCTPep ID DCTPep04431

Peptide Name Cecropin A (1-7)+Melittin (2-9)-C, CAMA

Sequence KWKLFKKIGAVLKVLC

Sequence Length 16

UniProt ID P01507

PubChem CID Not available

Origin Synthetic

Type Synthetic peptide

Classification

Cancer therapy related peptides

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID Not available

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C92H156N22O17S1

Absent amino acids DEHMNPQRSTY

Theoretical pI 10.20

Acidic residues 0

Basic residues 5

Polar residues 2

Molecular weight (Average) 1874.45

Molecular weight (Monoisotopic) 1873.17

Common amino acids K

Net charge 5

Instability index (II) -26.55

Aliphatic index 140.00

Grand average of hydropathicity (GRAVY) 0.662

Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 2.934, assuming all pairs of Cys residues form cystines
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 2.934, assuming all Cys residues are reduced

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 34528343

Title Antibacterial efficacy of in-house designed cell-penetrating peptide against multi-drug resistant strains of Salmonella Enteritidis and Salmonella Typhimurium

Doi Not available

Year 2022

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available

External Code

DBAASP ID 19778