Romo1 (58-78)[T2,9K;Q5K;S6K;M18del]
General Information
DCTPep ID DCTPep04459
Peptide Name Romo1 (58-78)[T2,9K;Q5K;S6K;M18del]
Sequence KKMMKKGGKFGTFMAIGGIR
Sequence Length 20
UniProt ID P60603
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C98H168N28O22S3
Absent amino acids CDEHLNPQSVWY
Theoretical pI 11.39
Acidic residues 0
Basic residues 6
Polar residues 6
Molecular weight (Average) 2186.77
Molecular weight (Monoisotopic) 2185.2
Common amino acids GK
Net charge 6
Instability index (II) 32.06
Aliphatic index 44.00
Grand average of hydropathicity (GRAVY) -0.230
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34361008
Title A Novel Peptide Derived from the Transmembrane Domain of Romo1 Is a Promising Candidate for Sepsis Treatment and Multidrug-Resistant Bacteria
Doi Not available
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 19981