Romo1 (58-78)[T2,9K;Q5K;S6K;M18del]

General Information


DCTPep ID  DCTPep04459

Peptide Name   Romo1 (58-78)[T2,9K;Q5K;S6K;M18del]

Sequence  KKMMKKGGKFGTFMAIGGIR

Sequence Length  20

UniProt ID  P60603 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C98H168N28O22S3

Absent amino acids  CDEHLNPQSVWY

Theoretical pI  11.39

Acidic residues  0

Basic residues  6

Polar residues  6

Molecular weight (Average)  2186.77

Molecular weight (Monoisotopic)  2185.2

Common amino acids  GK

Net charge  6

Instability index (II)  32.06

Aliphatic index  44.00

Grand average of hydropathicity (GRAVY)  -0.230

Half Life 
  1.3 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  3 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 34361008

Title  A Novel Peptide Derived from the Transmembrane Domain of Romo1 Is a Promising Candidate for Sepsis Treatment and Multidrug-Resistant Bacteria

Doi Not available

Year  2021

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  19981

DCTPep is developed by Dr.Zheng's team.