This work is licensed under a Creative Commons Attribution 4.0 International License.
Latarcin-3a, Ltc-3a
General Information
DCTPep ID DCTPep04461
Peptide Name Latarcin-3a, Ltc-3a
Sequence SWKSMAKKLKEYMEKLKQRA
Sequence Length 20
UniProt ID Q1ELU3
PubChem CID 49777296
Origin Animalia
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C111H187N31O29S2
Absent amino acids CDFGHINPTV
Theoretical pI 10.12
Acidic residues 2
Basic residues 7
Polar residues 3
Molecular weight (Average) 2484.02
Molecular weight (Monoisotopic) 2482.36
Common amino acids K
Net charge 5
Instability index (II) 32.5
Aliphatic index 49.00
Grand average of hydropathicity (GRAVY) -1.360
Half Life
1.9 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 2.814
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 36212827
Title First generation of multifunctional peptides derived from latarcin-3a from Lachesana tarabaevi spider toxin
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20021
This work is licensed under a Creative Commons Attribution 4.0 International License.