This work is licensed under a Creative Commons Attribution 4.0 International License.
Latarcin-3a (5-17) [M5,13L; K17V]
General Information
DCTPep ID DCTPep04462
Peptide Name Latarcin-3a (5-17) [M5,13L; K17V]
Sequence LAKKLKEYLEKLV
Sequence Length 13
UniProt ID Q1ELU3
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C75H131N17O19
Absent amino acids CDFGHIMNPQRSTW
Theoretical pI 9.40
Acidic residues 2
Basic residues 4
Polar residues 1
Molecular weight (Average) 1574.97
Molecular weight (Monoisotopic) 1573.98
Common amino acids KL
Net charge 2
Instability index (II) -10.36
Aliphatic index 150.00
Grand average of hydropathicity (GRAVY) -0.208
Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.946
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 36212827
Title First generation of multifunctional peptides derived from latarcin-3a from Lachesana tarabaevi spider toxin
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20022
This work is licensed under a Creative Commons Attribution 4.0 International License.