This work is licensed under a Creative Commons Attribution 4.0 International License.
Latarcin-3a (5-17) [M5,13L; A6I; E14K; K17I]
General Information
DCTPep ID DCTPep04463
Peptide Name Latarcin-3a (5-17) [M5,13L; A6I; E14K; K17I]
Sequence LIKKLKEYLKKLI
Sequence Length 13
UniProt ID Q1ELU3
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C80H144N18O17
Absent amino acids ACDFGHMNPQRSTVW
Theoretical pI 10.00
Acidic residues 1
Basic residues 5
Polar residues 1
Molecular weight (Average) 1630.13
Molecular weight (Monoisotopic) 1629.1
Common amino acids K
Net charge 4
Instability index (II) -23.42
Aliphatic index 180.00
Grand average of hydropathicity (GRAVY) -0.008
Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.914
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 36212827
Title First generation of multifunctional peptides derived from latarcin-3a from Lachesana tarabaevi spider toxin
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20023
This work is licensed under a Creative Commons Attribution 4.0 International License.