This work is licensed under a Creative Commons Attribution 4.0 International License.
General Information
DCTPep ID DCTPep04483
Peptide Name
Sequence GGGGRGDRGDLPETGGS
Sequence Length 17
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: Gly1<--->Ser17
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C59H97N23O26
Absent amino acids ACFHIKMNQVWY
Theoretical pI 4.56
Acidic residues 3
Basic residues 2
Polar residues 10
Molecular weight (Average) 1544.56
Molecular weight (Monoisotopic) 1543.7
Common amino acids G
Net charge -1
Instability index (II) 40.58
Aliphatic index 22.94
Grand average of hydropathicity (GRAVY) -1.294
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28351594
Title New potent and selective αvβ3 integrin ligands: Macrocyclic peptides containing RGD motif synthesized by sortase A-mediated ligation
Doi 10.1016/j.bmcl.2017.03.035
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20072
This work is licensed under a Creative Commons Attribution 4.0 International License.