This work is licensed under a Creative Commons Attribution 4.0 International License.
Nocardiotide A
General Information
DCTPep ID DCTPep04485
Peptide Name Nocardiotide A
Sequence AWIWLV
Sequence Length 6
UniProt ID Not available
PubChem CID Not available
Origin Bacteria
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: Ala1<--->Val6
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C42H58N8O7
Absent amino acids CDEFGHKMNPQRSTY
Theoretical pI 5.57
Acidic residues 0
Basic residues 0
Polar residues 0
Molecular weight (Average) 786.97
Molecular weight (Monoisotopic) 786.44
Common amino acids W
Net charge 0
Instability index (II) 28.9
Aliphatic index 195.00
Grand average of hydropathicity (GRAVY) 2.083
Half Life
4.4 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 13.978
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30134565
Title New Cytotoxic Cyclic Peptide from the Marine Sponge-Associated Nocardiopsis sp UR67
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20074
This work is licensed under a Creative Commons Attribution 4.0 International License.