Hm-AMP2
General Information
DCTPep ID DCTPep04509
Peptide Name Hm-AMP2
Sequence EKRWRRLIFNYF
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C83H122N24O17
Absent amino acids ACDGHMPQSTV
Theoretical pI 10.90
Acidic residues 1
Basic residues 4
Polar residues 2
Molecular weight (Average) 1728.03
Molecular weight (Monoisotopic) 1726.94
Common amino acids R
Net charge 3
Instability index (II) 131.8
Aliphatic index 65.00
Grand average of hydropathicity (GRAVY) -1.058
Half Life
1 hours (mammalian reticulocytes, in vitro).
30 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 4.045
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Non-toxic antimicrobial peptide Hm-AMP2 from leech metagenome
Doi Not available
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20171