This work is licensed under a Creative Commons Attribution 4.0 International License.
Hm-AMP8
General Information
DCTPep ID DCTPep04511
Peptide Name Hm-AMP8
Sequence RAVIYKIPYNAIASRWIIAPKKC
Sequence Length 23
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C126H204N34O28S1
Absent amino acids DEFGHLMQT
Theoretical pI 10.19
Acidic residues 0
Basic residues 5
Polar residues 5
Molecular weight (Average) 2675.28
Molecular weight (Monoisotopic) 2673.53
Common amino acids I
Net charge 5
Instability index (II) 46.27
Aliphatic index 114.78
Grand average of hydropathicity (GRAVY) 0.204
Half Life
1 hours (mammalian reticulocytes, in vitro).
2 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 8480
Abs 0.1% (=1 g/l) 3.170, assuming all pairs of Cys residues form cystines
Ext. coefficient 8480
Abs 0.1% (=1 g/l) 3.170, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Non-toxic antimicrobial peptide Hm-AMP2 from leech metagenome
Doi Not available
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20177
This work is licensed under a Creative Commons Attribution 4.0 International License.