Dianthin E

General Information


DCTPep ID  DCTPep04515

Peptide Name   Dianthin E

Sequence  GPISFV

Sequence Length  6

UniProt ID  Not available

PubChem CID  Not available

Origin  Plantae

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  NCB: Gly1<--->Val6

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C30H46N6O8

Absent amino acids  ACDEHKLMNQRTWY

Theoretical pI  5.52

Acidic residues  0

Basic residues  0

Polar residues  2

Molecular weight (Average)  618.73

Molecular weight (Monoisotopic)  618.34

Common amino acids  FGIPSV

Net charge  0

Instability index (II)  8.33

Aliphatic index  113.33

Grand average of hydropathicity (GRAVY)  1.450

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 15387653

Title  New cytotoxic cyclic peptides and dianthramide from Dianthus superbus

Doi Not available

Year  2004

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  20237

DCTPep is developed by Dr.Zheng's team.