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HG2
General Information
DCTPep ID DCTPep04517
Peptide Name HG2
Sequence MKKLLLILFCLALALAGCKKAP
Sequence Length 22
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys10<--->Cys18
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C111H196N26O23S3
Absent amino acids DEHNQRSTVWY
Theoretical pI 9.70
Acidic residues 0
Basic residues 4
Polar residues 3
Molecular weight (Average) 2359.12
Molecular weight (Monoisotopic) 2357.41
Common amino acids L
Net charge 4
Instability index (II) 31.95
Aliphatic index 160.00
Grand average of hydropathicity (GRAVY) 1.382
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.053, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 35835775
Title In silico identification of two peptides with antibacterial activity against multidrug-resistant Staphylococcus aureus
Doi Not available
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20288
This work is licensed under a Creative Commons Attribution 4.0 International License.