This work is licensed under a Creative Commons Attribution 4.0 International License.
Ocellatin-3N [D4K,A18K]
General Information
DCTPep ID DCTPep04523
Peptide Name Ocellatin-3N [D4K,A18K]
Sequence GIFKVLKNLAKGVITSLKS
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C94H166N24O24
Absent amino acids CDEHMPQRWY
Theoretical pI 10.48
Acidic residues 0
Basic residues 4
Polar residues 6
Molecular weight (Average) 2016.5
Molecular weight (Monoisotopic) 2015.25
Common amino acids K
Net charge 4
Instability index (II) -20.78
Aliphatic index 138.42
Grand average of hydropathicity (GRAVY) 0.589
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 36426386
Title Antimicrobial, cytotoxic, and insulin-releasing activities of the amphibian host-defense peptide ocellatin-3N and its L-lysine-substituted analogs
Doi Not available
Year 2022
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20349
This work is licensed under a Creative Commons Attribution 4.0 International License.