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Transmembrane protein (17-35), RCB-1
General Information
DCTPep ID DCTPep04564
Peptide Name Transmembrane protein (17-35), RCB-1
Sequence ARCCLVMPVPPFACVKFCS
Sequence Length 19
UniProt ID B9T5G6
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID 2MTM
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys3<--->Cys14; Cys4<--->Cys18
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C92H147N23O21S5
Absent amino acids DEGHINQTWY
Theoretical pI 8.56
Acidic residues 0
Basic residues 2
Polar residues 5
Molecular weight (Average) 2071.62
Molecular weight (Monoisotopic) 2069.97
Common amino acids C
Net charge 2
Instability index (II) 100.93
Aliphatic index 76.84
Grand average of hydropathicity (GRAVY) 1.237
Half Life
4.4 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 250
Abs 0.1% (=1 g/l) 0.121, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26509914
Title Synthesis, Structural Characterization, and Bioactivity of the Stable Peptide RCB-1 from Ricinus communis
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20587
This work is licensed under a Creative Commons Attribution 4.0 International License.