This work is licensed under a Creative Commons Attribution 4.0 International License.
General Information
DCTPep ID DCTPep04571
Peptide Name
Sequence LKLKLKLTGKLKLKL
Sequence Length 15
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C84H161N21O17
Absent amino acids ACDEFHIMNPQRSVWY
Theoretical pI 10.70
Acidic residues 0
Basic residues 6
Polar residues 2
Molecular weight (Average) 1737.33
Molecular weight (Monoisotopic) 1736.24
Common amino acids L
Net charge 6
Instability index (II) -64.25
Aliphatic index 182.00
Grand average of hydropathicity (GRAVY) 0.140
Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34506975
Title Manipulating turn residues on de novo designed β-hairpin peptides for selectivity against drug-resistant bacteria
Doi 10.1016/j.actbio.2021.09.004
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20601
This work is licensed under a Creative Commons Attribution 4.0 International License.