General Information


DCTPep ID  DCTPep04574

Peptide Name  

Sequence  LKLKLKINGKKLKLKL

Sequence Length  16

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C90H172N24O18

Absent amino acids  ACDEFHMPQRSTVWY

Theoretical pI  10.78

Acidic residues  0

Basic residues  7

Polar residues  2

Molecular weight (Average)  1878.51

Molecular weight (Monoisotopic)  1877.33

Common amino acids  K

Net charge  7

Instability index (II)  -63.69

Aliphatic index  170.62

Grand average of hydropathicity (GRAVY)  -0.244

Half Life 
  5.5 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 34506975

Title  Manipulating turn residues on de novo designed β-hairpin peptides for selectivity against drug-resistant bacteria

Doi 10.1016/j.actbio.2021.09.004

Year  2021

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  20604

DCTPep is developed by Dr.Zheng's team.