This work is licensed under a Creative Commons Attribution 4.0 International License.
General Information
DCTPep ID DCTPep04574
Peptide Name
Sequence LKLKLKINGKKLKLKL
Sequence Length 16
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C90H172N24O18
Absent amino acids ACDEFHMPQRSTVWY
Theoretical pI 10.78
Acidic residues 0
Basic residues 7
Polar residues 2
Molecular weight (Average) 1878.51
Molecular weight (Monoisotopic) 1877.33
Common amino acids K
Net charge 7
Instability index (II) -63.69
Aliphatic index 170.62
Grand average of hydropathicity (GRAVY) -0.244
Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34506975
Title Manipulating turn residues on de novo designed β-hairpin peptides for selectivity against drug-resistant bacteria
Doi 10.1016/j.actbio.2021.09.004
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 20604
This work is licensed under a Creative Commons Attribution 4.0 International License.