This work is licensed under a Creative Commons Attribution 4.0 International License.
Aurein 1.1
General Information
DCTPep ID DCTPep04663
Peptide Name Aurein 1.1
Sequence GLFDIIKKIAESI
Sequence Length 13
UniProt ID P82386
PubChem CID Not available
Origin Litoria aurea
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Amidation
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C68H115N15O19
Absent amino acids CHMNPQRTVWY
Theoretical pI 6.07
Acidic residues 2
Basic residues 2
Polar residues 2
Molecular weight (Average) 1446.75
Molecular weight (Monoisotopic) 1445.85
Common amino acids I
Net charge 0
Instability index (II) 20.48
Aliphatic index 157.69
Grand average of hydropathicity (GRAVY) 0.800
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 18957441
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 15203252
Title Not available
Doi Not available
Year Not available
Literature 3
Pubmed ID 10951191
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
CancerPPD ID 4404
This work is licensed under a Creative Commons Attribution 4.0 International License.