Aurein 2.2

General Information


DCTPep ID  DCTPep04666

Peptide Name   Aurein 2.2

Sequence  GLFDIVKKVVGALGSL

Sequence Length  16

UniProt ID  P82389 

PubChem CID  Not available

Origin  Litoria aurea

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Amidation

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C76H130N18O20

Absent amino acids  CEHMNPQRTWY

Theoretical pI  8.59

Acidic residues  1

Basic residues  2

Polar residues  4

Molecular weight (Average)  1615.98

Molecular weight (Monoisotopic)  1614.97

Common amino acids  GLV

Net charge  1

Instability index (II)  -5.94

Aliphatic index  158.12

Grand average of hydropathicity (GRAVY)  1.238

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 21144817

Title  Not available

Doi Not available

Year  Not available

Literature 2

Pubmed ID 18957441

Title  Not available

Doi Not available

Year  Not available

Literature 3

Pubmed ID 15203252

Title  Not available

Doi Not available

Year  Not available

Literature 4

Pubmed ID 10951191

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRAMP ID  DRAMP01609

CancerPPD ID  4408

DBAASP ID 

DCTPep is developed by Dr.Zheng's team.